Curcumaromins A,B, and C,Three Novel Curcuminoids from Curcuma aromatica |
| |
| Authors: | Xiang‐Dong Qin Yan Zhao Yuan Gao Fu‐Cai Ren Shu Yang Fei Wang |
| |
| Institution: | 1. College of Basic Science and Information Engineering, Yunnan Agricultural University, Kunming 650201, P.?R. China (phone/fax: +86‐871‐65226191);2. BioBioPha Co., Ltd., Kunming 650201, P.?R. China, (phone: +86‐871‐65215193;3. fax: +86‐871‐65215563) |
| |
| Abstract: | Three novel curcuminoids, curcumaromins A–C ( 1 – 3 , resp.), along with a known compound, longiferone B ( 4 ) were isolated from Curcuma aromatica Salisb . The structures of the new compounds were elucidated as (1E,4Z,6E)‐5‐hydroxy‐7‐{4‐hydroxy‐3‐(1R*,6R*)‐3‐methyl‐6‐(propan‐2‐yl)cyclohex‐2‐en‐1‐yl)phenyl}‐1‐(4‐hydroxyphenyl)hepta‐1,4,6‐trien‐3‐one ( 1 ), 2,3‐dihydro‐2‐(4‐hydroxyphenyl)‐6‐(E)‐2‐(4‐hydroxyphenyl)ethenyl]‐5‐(1R*,6R*)‐3‐methyl‐6‐(propan‐2‐yl)cyclohex‐2‐en‐1‐yl]‐4H‐pyran‐4‐one ( 2 ), and (1E,6E)‐1,7‐bis(4‐hydroxyphenyl)‐4‐(1R*,6R*)‐3‐methyl‐6‐(propan‐2‐yl)cyclohex‐2‐en‐1‐yl]hepta‐1,6‐diene‐3,5‐dione ( 3 ) on the basis of spectroscopic analysis. Curcumaromins A–C ( 1 – 3 ) represented the first examples of menthane monoterpene‐coupled curcuminoids. The known compound, longiferone B ( 4 ), was the first daucane sesquiterpene isolated from the genus Curcuma. |
| |
| Keywords: | Curcuminoids Curcumaromins A – C Curcuma aromatica |
|
|
