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Synthesis of indoles from pyridinium salts. 4. Ketimines in the synthesis of indoles from 3-nitropyridinium salts
Authors:M. A. Yurovskaya  A. Z. Afanas'ev  V. A. Chertkov  É. M. Gizatullina  Yu. G. Bundel'
Affiliation:(1) M. V. Lomonosov Moscow State University, 119899 Moscow
Abstract:The possibility of using certain ketimines in place of mixtures of ketone and amine in the synthesis of indoles from 3-nitropyridinium salts has been demonstrated. The use of ketimines leads, in many cases, to increased yields of indoles and simplifies their isolation. It has been established that the rate of indole formation is considerably increased in polar aprotic solvents.For Communication 3, see [1].Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 12, pp. 1625–1628, December, 1987.
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