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Microsomal and photochemical oxidation of aflatoxin B1 |
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| Authors: | B L Sergeev S P Bogovski? T I Ve?debaum R Kh Tanner I N Shevchuk |
| Abstract: | The UV irradiation (lambda = 362 nm) of aflatoxin B1 (AfB1) dissolved in water resulted in the formation of an oxidized product. The process was not inhibited by ionol, a routine inhibitor of the radical processes. The oxidized product was not found in the system where AfB1 was metabolized by the 3-methylcholanthrene-activated rat liver microsomes. It is suggested that the product is identical with 2,3-dihydrodiol of AfB1. |
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