溶胶-凝胶法制备高热稳定性的毛细管气相色谱柱

毛细管气相色谱柱的传统制备工艺都较为复杂，周期较长，同时固定相和石英毛细管内壁间通常并无化学键生成，在较高温度下使用时固定相的流失严重，导致这类色谱柱的最高允许使用温度不很高．溶胶-凝胶法是一种快速有效的制备色谱柱的新技术，近年来经常应用于高效液相色谱、毛细管电色谱和固定相微萃取等分析化学的许多领域．在气相色谱方面，溶胶-凝胶端羟基聚硅氧烷柱、溶胶-凝胶聚乙二醇柱和溶胶-凝胶开链冠醚柱已相继制备出来，在用溶胶-凝胶

Preparation of Capillary Gas Chromatographic Columns with High Thermal Stability by Sol-gel Method

Perethylated-β-CD, perpentylated-β-CD and 2,6-di-O-pentyl-β-CD were coated onto the fused silica capillary by sol-gel process. The thermal stability of the three sol-gel columns was investigated by pyrolysis gas chromatography(PyGC). The PyGC results show that the sol-gel CDs columns have an outstanding thermal stability, compared with the conventional CDs columns. The temperature of preliminary pyrolysis of the CDs in sol-gel net can be as high as 300 ℃, of the alkylated-β-CDs are at 200℃. The column performances were also studied. The results show that the sol-gel CDs columns have a good separation ability to the disubstituted benzene isomers such as cresols and xylene isomers.