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Enzymatic resolution of (±)-cis-2-aminocyclopentanol and (±)-cis-2-aminocyclohexanol |
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| Authors: | Amparo Luna Covadonga Astorga Ferenc Fülöp Vicente Gotor |
| Institution: | a Departamento de Química Orgánica e Inorgánica, Facultad de Química, Universidad de Oviedo 33071 Oviedo Spain b Institute of Pharmaceutical Chemistry, Albert Szent-Györgyi Medical University H-6701 Szeged, POB 121 Hungary |
| Abstract: | (±)-cis-N-Benzyloxycarbonyl-2-aminocyclopentanol was efficiently resolved by O-acylation with Pseudomonas cepacia lipase, as was (±)-cis-N-benzyloxycarbonyl-2-aminocyclohexanol when Candida antarctica lipase was used. |
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