Fletcher Stuckey Pratt Chair in Engineering, Departments of Chemical Engineering and Biomedical Engineering, University of Texas at Austin, 1 University Station C0400, Austin, TX 78712‐1062, USA
Abstract:
CD is used to clearly show the negative impact of common ligands on the overall conformation of BSA, a typical protein template in macromolecularly imprinted polymers. This change occurs at concentrations far lower than those generally used in the literature. These findings are important as they offer insight into a potential fundamental reason for the lack of success in protein imprinting to date despite significant interest from the scientific community.
