1. Department of Materials Science and Engineering, Gwangju Institute of Science and Technology (GIST), 1 Oryong‐dong, Buk‐gu, Gwangju 500‐712, South Korea;2. Current address: Physikalisches Institut, Universit?t Münster, Wilhelm Klemm‐Str. 10, 48149 Münster, Germany;3. Department of Nanobio Materials and Electronics (WCU), and Institute of Medical System Engineering, Gwangju Institute of Science and Technology (GIST), 1 Oryong‐dong, Buk‐gu, Gwangju 500‐712, South Korea
Abstract:
Water‐soluble, PAX‐loaded carbon nanotubes are fabricated by employing a synthetic polyampholyte, PDM. To investigate the suitability of the polyampholyte and the nanotubes as drug carriers, different cellular interactions such as the human epithelial Caco‐2 cells viability, their effect on the cell growth, and the change in the transepithelial electrical resistance in Caco‐2 cells are studied. The resulting complex is found to exhibit an effective anti‐cancer effect against colon cancer cells and an increased the reduction of the electrical resistance in the Caco‐2 cells when compared to the precursor PAX.
