Slow relaxation of longitudinal multispin orders in weakly and strongly coupled two‐spin systems |
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| Authors: | Loyola D'Silva Arunima Pola Prasanta Dutta Gary V Martinez Peter Sprenger Robert J Gillies Philip W Kuchel S Sendhil Velan |
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| Institution: | 1. Laboratory of Molecular Imaging, Singapore Bioimaging Consortium, A*STAR, , Singapore;2. Clinical Imaging Research Centre, NUS‐A*STAR, , Singapore;3. Imaging Program, Moffitt Cancer Center & Research Institute, , Tampa, FL, USA;4. Bruker BioSpin AG, , Bangkok, Thailand |
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| Abstract: | Longitudinal multispin order (LOMO) corresponds to a nonequilibrium population distribution in spin systems that exhibit scalar (J), dipolar, or quadrupolar coupling. We investigated the relaxation of longitudinal two‐spin order (2‐LOMO) in systems that had either weakly or strongly J‐coupled spins. Our results indicated longer relaxation times for the 2‐LOMO state compared with the corresponding longitudinal single‐spin state (1‐LOMO). Accessing nuclear spin states that have relaxation times longer than T1, without the use of external contrast agents, is potentially useful for in vivo imaging and also for studying systems using dynamically hyperpolarized nuclear spins where longer life times are sought to increase the time available to study (bio)chemical events. Copyright © 2012 John Wiley & Sons, Ltd. |
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| Keywords: | longitudinal multispin order (LOMO) nuclear magnetic relaxation strong scalar coupling weak scalar coupling nuclear magnetic resonance (NMR) density matrix |
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