| 4-(对取代苯基)-2-[2-(取代苯基)呋喃-4-甲酰胺]-1',3',4'-均三唑[1,2-d]-1,3,4-噻二唑类衍生物的合成和生物活性 |
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| 引用本文： | 薛思佳,柴安,蔡志娟,卞王东. 4-(对取代苯基)-2-[2-(取代苯基)呋喃-4-甲酰胺]-1',3',4'-均三唑[1,2-d]-1,3,4-噻二唑类衍生物的合成和生物活性[J]. 有机化学, 2008, 28(3): 494-497 |
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| 作者姓名： | 薛思佳 柴安 蔡志娟 卞王东 |
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| 作者单位： | 上海师范大学生命与环境科学学院,上海,200234 |
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| 基金项目： | 国家自然科学基金，上海市重点学科建设项目 |
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| 摘 要： | 以1-氨基-5-巯基-2-(对取代苯基)-1,3,4-均三唑和5-取代苯基-2-呋喃甲酰异硫氰酸酯为原料, 合成了10个未见文献报道的含苯环连呋喃的均三唑并噻二唑类衍生物, 通过元素分析, 1H NMR, IR和MS确定化合物的结构, 初步生物活性测试表明标题化合物具有一定的除草活性.
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| 关 键 词： | 酰胺 1,3,4-均三唑并[1,2-d]-1,3,4-噻二唑 合成 除草活性 |
| 收稿时间： | 2007-06-18 |
| 修稿时间： | 2007-08-20 |
Synthesis and Biological Activity of 4-(p-Substituted phenyl)-2-[2-(substituted phenyl)-furoyl-4-amido]-1',3',4'-triazolo[1,2-d]-1,3,4-thiadiazoles |
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| XUE Si-Jia,CHAI An,CAI Zhi-Juan,BIAN Wang-Dong. Synthesis and Biological Activity of 4-(p-Substituted phenyl)-2-[2-(substituted phenyl)-furoyl-4-amido]-1',3',4'-triazolo[1,2-d]-1,3,4-thiadiazoles[J]. Chinese Journal of Organic Chemistry, 2008, 28(3): 494-497 |
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| Authors: | XUE Si-Jia CHAI An CAI Zhi-Juan BIAN Wang-Dong |
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| Affiliation: | (College of Life and Environment Science, Shanghai Normal University, Shanghai 200234) |
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| Abstract: | Ten unreported compounds 4-(p-substituted phenyl)-2-[2-(substituted phenyl)-furoyl-4-amido]-1',3',4'-triazolo[1,2-d]-1,3,4-thiadiazoles were synthesized by the reaction of 1-amino-5-mercapto-2-(p-substituted phenyl)-1,3,4-triazoles with 5-(substituted phenyl)-2-furoyl isothiocyanates. Their structures were determined by elemental analysis, 1H NMR, IR and MS techniques, and preliminary bio-logical test indicated that the compounds had some herbicidal activities. |
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| Keywords: | amide 1,3,4-triazolo[1,2-d]-1,3,4-thiadiazole synthesis herbicidal activity |
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