| 不同反应体系中(S)-1-(4-甲氧基)-苯基乙醇的不对称生物合成 |
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| 引用本文： | 汪薇,宗敏华,娄文勇.不同反应体系中(S)-1-(4-甲氧基)-苯基乙醇的不对称生物合成[J].催化学报,2011,32(6):1003-1010. |
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| 作者姓名： | 汪薇 宗敏华 娄文勇 |
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| 作者单位： | 仲恺农业工程学院轻工食品学院;华南理工大学应用生物催化实验室; |
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| 基金项目： | 国家自然科学基金(20602013,20876059); 仲恺农业工程学院引进优秀人才科研启动基金(G2360314)~~ |
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| 摘 要： | 在不同反应体系中,研究了固定化红酵母细胞催化对甲氧基苯乙酮不对称还原合成(S)-1-(4-甲氧基)-苯基乙醇的反应.结果表明,在含离子液体的混合反应体系和双相反应体系中,该不对称还原反应的效率得到了不同程度的提高.此外,离子液体中阴阳离子类型对该反应的影响较大,特定阴阳离子间的匹配对同定化红酵母细胞发挥最佳催化效果至关...
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| 关 键 词： | 对甲氧基苯乙酮 1-(4-甲氧基)-苯基乙醇 离子液体 催化 微生物细胞 不对称生物合成 |
Asymmetric Biosynthesis of (S)-1-(4-Methoxyphenyl)ethanol in Various Reaction Systems |
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| WANG Wei,ZONG Minhua,LOU Wenyong.Asymmetric Biosynthesis of (S)-1-(4-Methoxyphenyl)ethanol in Various Reaction Systems[J].Chinese Journal of Catalysis,2011,32(6):1003-1010. |
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| Authors: | WANG Wei ZONG Minhua LOU Wenyong |
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| Institution: | WANG Wei1,ZONG Minhua2,*,LOU Wenyong2 1College of Light Industry and Food Science,ZhongKai University of Agriculture and Engineering,Guangzhou 510225,Guangdong,China 2Laboratory of Applied Biocatalysis,South China University of Technology,Guangzhou 510640,China |
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| Abstract: | The biocatalytic enantioselective reduction of 4-methoxyacetophenone to (S)-1-(4-methoxyphenyl)ethanol was studied.The efficiency of the reaction was improved to different extents when an ionic liquid-containing co-solvent system and an ionic liquids/bufffer biphasic system were used.The catalytic performance of the biocatalyst depended not only on the types of the anions and cations in the ionic liquids but also on their combination. |
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| Keywords: | 4-methoxyacetophenone 1-(4-methoxyphenyl)ethanol ionic liquid catalysis microbial cell asymmetric biosynthesis |
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