Gas chromatography of epinephrine and norepinephrine after derivatization with chloroformates in aqueous media |
| |
Authors: | Olle Gyllenhaal, Lars Johansson,J rgen Vessman |
| |
Affiliation: | Olle Gyllenhaal, Lars Johansson,Jörgen Vessman |
| |
Abstract: | Optimal conditions for the reaction of alkyl chloroformates with epinephrine and norepinephrine in aqueous solution have been evaluated. The maximal yield with 0.06 M methyl chloroformate was in the pH range 7.0–8.5. The derivatives formed are isolated by extraction with methylene chloride and gas chromatographed on 3% QF-1 with a nitrogen-selective detector after trimethylsilylation of the alcohol group. |
| |
Keywords: | |
本文献已被 ScienceDirect 等数据库收录! |