|
|||||
|
|
Solid-phase Synthesis of Thymopentin Derivative and Its Immune Regulatory Activity |
|
| Authors: | LIANG Yong-tao MI Hao-yu WANG Ming-zhe YU Li-ya LIU Zhong-hui WANG En-si College of Life Science Jilin University Changchun P R China Changchun University of Chinese Medicine Changchun College of Basic Medical Sciences College of Phamacy |
| Institution: | [1]College of Life Science, Jilin University, Changchun 130021, P R. China [2]Changchun University of Chinese Medicine, Changehun 130061, P. R. China [3]College of Basic Medical Sciences, Changchun 130021, P. R. China [4]College of Phamacy, Jilin University, Changchun 130021, P. R. China |
| Abstract: | Thymopentin derivative(septapeptide) was prepared by means of the solid-phase peptide synthesis method in which stepwise and segment condensations were involved.The structures of the key intermediate and target molecule were confirmed by ESI-MS,elementary analysis,IR,1H NMR and 13C NMR spectrometries in our experiments.In this study,the authors found that both thymopentin derivetive(septapeptide) and thymopentin could promote T cell proliferation and increase of E-rose fomation cells. |
| Keywords: | Thymopentin derivative Peptide T cell |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |