分子马达五配位磷化学结构分析

分子马达运动的“动因”是研究分子马达的关键问题．目前无论是线性分子马达还是旋转分子马达的研究，由分子马达构象变化引起整个分子马达运动的理论得到普遍认可．分子马达与高能物质(特别是含磷物质)发生构象变化，例如ATP与分子马达部件上氨基酸的弱结合(Weak binding)、强结合(Binding)及释放(Release)等引起的构象变化，往往被用来解释分子马达运动的原因．其化学机理国际

Penta-coordinated Phosphorous Structure Analysis on Molecular Motors

The mechanisms of molecular motors are still unresolved problems. Based on our experiments on amino acids, the activated process of molecular motors was analyzed and original software using the method of penta-coordinated phosphorous structure was designed. Via the software, the hotspots from different molecular motors′ phosphorous activated area were obtained. It was found that the types of hotspots discovered with above methods were highly conserved. This founding provides new perspectives to study the intrinsic relationship of motion in molecular motors and also helps understanding the evolution of molecular motors.