Total synthesis of the potent antitumor polyketide (-)-callystatin A |
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Authors: | Dias Luiz C Meira Paulo R R |
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Affiliation: | Instituto de Química, Universidade Estadual de Campinas, UNICAMP, C. P. 6154, CEP 13084-971, Campinas, SP, Brazil. ldias@iqm.unicamp.br |
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Abstract: | A highly convergent and efficient total synthesis of the potent antitumor polyketide (-)-callystatin A is described. The synthesis required 19 steps from N-propionyl oxazolidinone 23 and produced the desired product in 3.5% overall yield. |
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