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Total synthesis of the potent antitumor polyketide (-)-callystatin A
Authors:Dias Luiz C  Meira Paulo R R
Affiliation:Instituto de Química, Universidade Estadual de Campinas, UNICAMP, C. P. 6154, CEP 13084-971, Campinas, SP, Brazil. ldias@iqm.unicamp.br
Abstract:A highly convergent and efficient total synthesis of the potent antitumor polyketide (-)-callystatin A is described. The synthesis required 19 steps from N-propionyl oxazolidinone 23 and produced the desired product in 3.5% overall yield.
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