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Triflic acid-promoted aza-Prins-Ritter reaction sequence: a novel synthesis of 4-amidopiperidine derivatives
Authors:BV Subba Reddy  K RameshAV Ganesh  GGKS Narayana KumarJS Yadav  René Grée
Institution:a Division of Organic Chemistry, Indian Institute of Chemical Technology, Hyderabad 500 007, India
b Université de Rennes 1, Laboratoire SCR, CNRS UMR 6226, Avenue du Général Leclerc, 35042 Rennes Cedex, France
Abstract:4-Amidopiperidine derivatives have been prepared for the first time in good yields and with high selectivity by means of aza-Prins-Ritter reaction sequence using 1.2 equiv of triflic acid under mild reaction conditions.
Keywords:aza-Prins-Ritter reaction  Triflic acid  Homoallylic amines  4-Amidopiperidines
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