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Neurophysiological and functional MRI evidence of reorganization of cortical motor areas in cerebral arteriovenous malformation |
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| Authors: | Francesca Caramia Ada Francia Caterina Mainero Emanuele Tinelli Maria Giuseppina Palmieri Claudio Colonnese Luigi Bozzao Maria Donatella Caramia |
| Affiliation: | 1. Department of Neurological Sciences, University of Rome “La Sapienza,” 00185 Rome, Italy;2. Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA;3. Department of Public Health, University of Rome “Tor Vergata”, Via Montpellier 1, 00133 Rome, Italy |
| Abstract: | Functional magnetic resonance imaging (fMRI) research has shown that brain arteriovenous malformations (AVMs) lead to reorganization of cortical motor areas. Since it is known that blood oxygenation level-dependent signal in fMRI may be influenced by the hemodynamic perturbation associated with the presence of the AVM, in the present study, a combined exploration with fMRI and transcranial magnetic stimulation was performed in a patient with a right rolandic AVM in order to explore the relationship between neuronal and hemodynamic activity. The combined protocol of investigation adopted in this study was able to provide significant information regarding neuronal activity of the different cortical areas that partake to post-lesional reorganization. |
| Keywords: | Cortical evoked potential fMRI Arteriovenous malformation |
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