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Chemical-genetic profile analysis of five inhibitory compounds in yeast |
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| Authors: | Md Alamgir Veronika Erukova Matthew Jessulat Ali Azizi Ashkan Golshani |
| Institution: | (1) Department of Biology, Carleton University, 1125 Colonel By Drive, K1 S 5B6 Ottawa, ON, Canada;(2) Ottawa Institute of System Biology, University of Ottawa, 451 Smyth Road, K1 H 8M5 Ottawa, ON, Canada;(3) Faculty of Medicine, University of Ottawa, 401 Smyth Road, K1 H 8L1 Ottawa, ON, Canada |
| Abstract: | BackgroundChemical-genetic profiling of inhibitory compounds can lead to identification of their modes of action. These profiles can help elucidate the complex interactions between small bioactive compounds and the cell machinery, and explain putative gene function(s). |
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