Iodine-catalyzed three-component reaction of quinazoline-2,5-diones with aldehydes and styrenes for the synthesis of allylamine derivatives |
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Authors: | Zhang Zhang Yu-Shan Zhang Zheng-Jun Quan Yu-Xia Da Xi-Cun Wang |
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Affiliation: | 1. Key Laboratory of Eco-Environment-Related Polymer Materials, Ministry of Education, China, Gansu 730070, PR China;2. Gansu Key Laboratory of Polymer Materials, College of Chemistry and Chemical Engineering, Northwest Normal University, Anning East Road 967#, Lanzhou, Gansu 730070, PR China |
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Abstract: | Iodine-catalyzed three component reaction of quinazoline-2,5-diones, aldehydes, and styrenes provides allylamine derivatives was described. Both paraformaldehyde and ethyl glyoxalate can be applied in this reaction with simple styrenes with high regioselectivity. |
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Keywords: | Iodine Allyamines Three-component reaction C&ndash C formation C&ndash N formation |
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