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Iodine-catalyzed three-component reaction of quinazoline-2,5-diones with aldehydes and styrenes for the synthesis of allylamine derivatives
Authors:Zhang Zhang  Yu-Shan Zhang  Zheng-Jun Quan  Yu-Xia Da  Xi-Cun Wang
Affiliation:1. Key Laboratory of Eco-Environment-Related Polymer Materials, Ministry of Education, China, Gansu 730070, PR China;2. Gansu Key Laboratory of Polymer Materials, College of Chemistry and Chemical Engineering, Northwest Normal University, Anning East Road 967#, Lanzhou, Gansu 730070, PR China
Abstract:Iodine-catalyzed three component reaction of quinazoline-2,5-diones, aldehydes, and styrenes provides allylamine derivatives was described. Both paraformaldehyde and ethyl glyoxalate can be applied in this reaction with simple styrenes with high regioselectivity.
Keywords:Iodine   Allyamines   Three-component reaction   C&ndash  C formation   C&ndash  N formation
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