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A simple method for desymmetrizing 1,1′-ferrocenedicarboxaldehyde |
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| Authors: | Andrew C. Benniston Dumitru Sirbu Constantin Turta Michael R. Probert William Clegg |
| Affiliation: | 1. Molecular Photonics Laboratory, School of Chemistry, Newcastle University, Newcastle upon Tyne NE1 7RU, UK;2. Institute of Chemistry, Academy of Sciences of Moldova, 3, Academiei str., Chisinau, Republic of Moldova;3. Crystallography Laboratory, School of Chemistry, Newcastle University, Newcastle upon Tyne NE1 7RU, UK |
| Abstract: | A simple chromatography-free method for desymmetrizing ferrocene is described starting from the readily available dialdehyde. Oxidation of 1,1′-ferrocenedicarboxaldehyde in a water/acetonitrile mixture with KMnO4 produced 1′-formyl-ferrocenecarboxylic acid. The same reaction carried out in a water/acetone mixture produced 1′-[(E)-3-oxo-but-1-enyl]-ferrocenecarboxylic acid. |
| Keywords: | Ferrocene Oxidation Desymmetrization Carboxylic acid Michael addition |
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