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A facile one-pot synthesis of 7-substituted pyrazolo[1,5-a]pyrimidines by base induced three-component reaction |
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| Authors: | Pallabi Saikia Partha Pratim KaishapRashmi Prakash Kommuri ShekarraoSanjib Gogoi Romesh C. Boruah |
| Affiliation: | Medicinal Chemistry Division, CSIR-North East Institute of Science and Technology, Jorhat 785006, India |
| Abstract: | The preparation of steroid/nonsteroid fused 7-substituted pyrazolo[1,5-a]pyrimidines is described by a one-pot reaction of steroidal/nonsteroidal ketones, aromatic aldehydes and 3-amino-1H-pyrazoles/5-amino-1H-pyrazoles in the presence of potassium tert-butoxide in good yield under reflux condition in ethanol. |
| Keywords: | Pyrazolo[1,5-a]pyrimidine Steroid Potassium tert-butoxide Heterocycle Amino-1H-pyrazole |
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