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A carbanion induced synthesis of highly congested pyrazole and imidazole containing heterocycles
Authors:Hardesh K. Maurya  Atul Gupta
Affiliation:Medicinal Chemistry Department, CSIR-Central Institute of Medicinal and Aromatic Plants, P.O. CIMAP, Kukrail Picnic spot Road, Lucknow 226015, India
Abstract:An efficient approach to the synthesis of highly congested di, penta and hexacyclic pyrazoles as well as imidazole fragment containing novel heterocyclic molecule has been developed through a carbanion induced transformation of suitably functionalized 2H-pyran-2-ones, benzo[h]chromene and thiochromeno[4,3-b]pyrans. Due to the presence of fluorescence, we report their prime application metal sensor as off/on switching in ferric ions.
Keywords:SJDBEROAEMAOJW-UHFFFAOYSA-N   NFJFJJLADCFCHO-UHFFFAOYSA-N   USQXBUWUQULKNW-UHFFFAOYSA-N   XHLHPRDBBAGVEG-UHFFFAOYSA-N   GABLTKRIYDNDIN-UHFFFAOYSA-N   CVQSWZMJOGOPAV-UHFFFAOYSA-N   OKHUUKHZUNKSQA-UHFFFAOYSA-N   TZJIDQOHLPCMHW-UHFFFAOYSA-N   VKXYXMOAYZYYTN-UHFFFAOYSA-N   YIRPINJCGYYKKK-UHFFFAOYSA-N   ZLRPLSMJQRKWFJ-UHFFFAOYSA-N   JWDNMYTZJBQWEO-UHFFFAOYSA-N   MQOKCYMCONEXNN-UHFFFAOYSA-N   UUFMVWCYVPTXBY-UHFFFAOYSA-N   KLNNSNLBVXCFFH-UHFFFAOYSA-N   HHDPUSZKOKUNER-UHFFFAOYSA-N   DBZSNHAWKDUAHX-UHFFFAOYSA-N   WKGWWEOUOLCYMQ-UHFFFAOYSA-N   SEYVCHLCXSBXGS-UHFFFAOYSA-N   NJZALRXUINMCTR-UHFFFAOYSA-N   IODRPGWCDHWXEG-UHFFFAOYSA-N   CHVMXHCSZAYZRO-UHFFFAOYSA-N   VMQQOVPKRMYULE-UHFFFAOYSA-N   UQVPJBHAADDXSM-UHFFFAOYSA-N   BWOVACANEIVHST-UHFFFAOYSA-N   RRXUDUYDBRWEOQ-UHFFFAOYSA-N   VWACCPBHUSAAJK-UHFFFAOYSA-N   VFYRIHUQJIDZTG-UHFFFAOYSA-N   BKBQPRPOPYRCFB-UHFFFAOYSA-N   KWOLFJPFCHCOCG-UHFFFAOYSA-N   FIGVJXMTQDHJMQ-UHFFFAOYSA-N   VOISDZHTKJQPAM-UHFFFAOYSA-N   ZVGCJBIDARLIMB-UHFFFAOYSA-N   LONGYNYRAPHNDS-UHFFFAOYSA-N   ZWKKHRLWUFOSPA-UHFFFAOYSA-N   STGYTXNBWMZKBA-UHFFFAOYSA-N   YUEINQRCAODONE-UHFFFAOYSA-N   TZTXWXHPBBTHJN-UHFFFAOYSA-N   BWQGFBUIBQJXBL-UHFFFAOYSA-N   CKUASGMDCIXRBF-UHFFFAOYSA-N   ZSXGLVDWWRXATF-UHFFFAOYSA-N   UPFBAUZYKBLCEO-ZRDIBKRKSA-N   NKPNESPVSMHQPA-ZRDIBKRKSA-N   WJNQRYCMQPMUDS-PKNBQFBNSA-N   XPAKBGQUORPCMO-PKNBQFBNSA-N   QXQPWPCSFNZDEU-JLHYYAGUSA-N   GZIVJULDDUFWSQ-PKNBQFBNSA-N   KXDAEFPNCMNJSK-UHFFFAOYSA-N   RLGJGDBTBWUXKU-UHFFFAOYSA-N   GMGFVDIZPIWNDY-UHFFFAOYSA-N   ICSNLGPSRYBMBD-UHFFFAOYSA-N
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