Domino synthesis of fused hexacyclic imidazoquinolinoacridinones catalyzed by CuI/l-proline |
| |
| Authors: | Chao Li Wen-Ting ZhangXiang-Shan Wang |
| |
| Institution: | School of Chemistry and Chemical Engineering, Jiangsu Key Laboratory of Green Synthesis for Functional Materials, Jiangsu Normal University, Xuzhou, Jiangsu 221116, PR China |
| |
| Abstract: | A three-component reaction of 2-halogenated aromatic aldehydes, 1H-benzod]imidazol-5-amine and cyclohexane-1,3-diones is described, and gives imidazoquinolinoacridinone derivatives in good yields catalyzed by CuI/l-proline. This Domino reaction constructs a fused hexacyclic skeleton in one-pot containing two new rings, six new bonds and an Ullmann-type C–N bond coupling reaction. |
| |
| Keywords: | Domino reaction Imidazoquinolinoacridine Ullmann reaction CuI |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
