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A new route to the synthesis of ellipticine quinone from isatin |
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| Authors: | Nagarajan Ramkumar Rajagopal Nagarajan |
| Affiliation: | School of Chemistry, University of Hyderabad, Hyderabad 500 046, India |
| Abstract: | 1-(2-Oxo-2-(pyridin-4-yl)ethyl)indoline-2,3-dione can be prepared and converted by treatment with sodium hydroxide into 2-isonicotinoyl-1H-indole-3-carboxylic acid as a key intermediate which can be transformed into ellipticine quinone in a two step sequence. |
| Keywords: | Alkaloids Rearrangement o-Lithiation Total synthesis Ellipticine quinone |
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