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[4+2] cycloaddition of intermediates generated from arynes and DMF |
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| Authors: | Eito Yoshioka Hirofumi TamenagaHideto Miyabe |
| Institution: | School of Pharmacy, Hyogo University of Health Sciences, Minatojima, Kobe 651-8530, Japan |
| Abstract: | The trapping reaction of the transient intermediate ortho-quinone methides, generated by the insertion of arynes into a carbon–oxygen double bond of DMF, with dienophiles was investigated. The 4+2] cycloaddition products were obtained when the diesters of acetylenedicarboxylic acid were employed as dienophiles. |
| Keywords: | Aryne Cycloaddition Amide Three-component reaction Acetylenedicarboxylic acid diester |
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