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Selective reduction of carbonyl groups in the presence of low-valent titanium reagents
Authors:Wei Lin  Ming-Hua HuXian Feng  Lei FuCheng-Pao Cao  Zhi-Bin Huang  Da-Qing Shi
Affiliation:Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123, PR China
Abstract:The chemoselective reduction of several structurally diverse compounds containing carbonyl groups was achieved in the presence of low-valent titanium reagents. This novel synthetic method provides easy access to highly selective reduction of carbonyl groups, and possesses several advantages including one-step procedure, convenient manipulation, good to excellent yields, and short reaction times.
Keywords:Chemoselective reduction   Carbonyl groups   Low-valent titanium reagent
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