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A facile method for the synthesis of steroidal and nonsteroidal 5-methyl pyrazolo[1,5-a]pyrimidines |
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| Authors: | Partha Pratim Kaishap Swagata BaruahKommuri Shekarrao Sanjib Gogoi Romesh C. Boruah |
| Affiliation: | Medicinal Chemistry Division, CSIR-North East Institute of Science and Technology, Jorhat 785006, India |
| Abstract: | The steroidal and nonsteroidal 5-methyl pyrazolo[1,5-a]pyrimidines were synthesized by the reaction of steroidal/nonsteroidal α,β-unsaturated ketones and 3-amino-1H-pyrazoles/5-amino-1H-pyrazoles in the presence of KOtBu in ethanol under reflux condition. |
| Keywords: | Pyrazolo[1,5-a]pyrimidine Steroid Potassium tert-butoxide Heterocycle Amino-1H-pyrazole |
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