Copper(I) 3-methylsalicylate,an efficient catalyst for N-arylation of heterocycles under moderate reaction conditions |
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| Authors: | Abdelbasset A Farahat David W Boykin |
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| Institution: | 1. Department of Chemistry, Georgia State University, Atlanta, GA 30303, United States;2. Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt |
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| Abstract: | Copper(I) 3-methylsalicylate mediates N-arylation reactions of both aliphatic and aromatic heterocycles under moderate reaction conditions. Both electron rich and electron poor aryl bromides and a diverse set of N-heterocycles were allowed to react and gave N-arylation products in high yields which demonstrated the efficiency and utility of this catalyst. |
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