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BODIPY‐Based Fluorescent Thermometer as a Lysosome‐Targetable Probe: How the Oligo(ethylene glycols) Compete Photoinduced Electron Transfer
Authors:Hua Wang  Dr. Yongquan Wu  Yanlin Shi  Pan Tao  Prof. Dr. Xing Fan  Prof. Dr. Xinyan Su  Prof. Dr. Gui‐Chao Kuang
Affiliation:1. Department of Polymer Materials, Shanghai University, Nanchen Road 333, 200444, Shanghai (P.R. China);2. Department of Chemistry, Fudan University, Handan Road 220, 200433, Shanghai (P.R. China);3. College of Chemistry and Chemical Engineering, Chongqing University, Shazheng Road 174, 400044, Chongqing (P.R. China)
Abstract:A novel BODIPY‐based fluorescent thermometer, which shows a lysosome‐targeting property, was successfully prepared. Due to the electron‐donating ability of the oligo(ethylene glycols), the photoinduced electron‐transfer pathway from morpholine to BODIPY dye is blocked. The fluorescence of the thermometer quenched by intramolecular rotation at room temperature was progressively enhanced during heating due to the increased microviscosity around the fluorophore.
Keywords:analytical methods  BODIPY  fluorescent probes  lysosome  electron transfer
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