BODIPY‐Based Fluorescent Thermometer as a Lysosome‐Targetable Probe: How the Oligo(ethylene glycols) Compete Photoinduced Electron Transfer |
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| Authors: | Hua Wang Dr Yongquan Wu Yanlin Shi Pan Tao Prof Dr Xing Fan Prof Dr Xinyan Su Prof Dr Gui‐Chao Kuang |
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| Institution: | 1. Department of Polymer Materials, Shanghai University, Nanchen Road 333, 200444, Shanghai (P.R. China);2. Department of Chemistry, Fudan University, Handan Road 220, 200433, Shanghai (P.R. China);3. College of Chemistry and Chemical Engineering, Chongqing University, Shazheng Road 174, 400044, Chongqing (P.R. China) |
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| Abstract: | A novel BODIPY‐based fluorescent thermometer, which shows a lysosome‐targeting property, was successfully prepared. Due to the electron‐donating ability of the oligo(ethylene glycols), the photoinduced electron‐transfer pathway from morpholine to BODIPY dye is blocked. The fluorescence of the thermometer quenched by intramolecular rotation at room temperature was progressively enhanced during heating due to the increased microviscosity around the fluorophore. |
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| Keywords: | analytical methods BODIPY fluorescent probes lysosome electron transfer |
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