A New Water‐Soluble Phosphorus‐Dipyrromethene and Phosphorus‐Azadipyrromethene Dye: PODIPY/aza‐PODIPY |
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| Authors: | Dr Xin‐Dong Jiang Jiuli Zhao Dongmei Xi Haifeng Yu Jian Guan Shuang Li Dr Chang‐Liang Sun Prof Dr Lin‐Jiu Xiao |
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| Institution: | 1. College of Applied Chemistry, Shenyang University of chemical Technology, Shenyang, 110142 (P.R. China);2. Center of Physical and Chemistry Test, Shenyang University of Chemical Technology, Shenyang 110142 (P.R. China) |
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| Abstract: | PODIPY and aza‐PODIPY have been successfully prepared by the treatment of dipyrromethene and azadipyrromethene with POCl3 in the presence of Et3N. The new PODIPY and aza‐PODIPY dyes are found to have photophysical properties. PODIPY and aza‐PODIPY are water‐soluble, and aza‐PODIPY is suited for labeling living Hep‐2 cells for imaging assays in the near‐infrared region. Molecular orbital calculations show that the increase in the HOMO–LUMO band gap for the lowest energy absorption bands is observed in the new phosphorus‐containing aza‐PODIPY, and the HOMO and LUMO energies of aza‐PODIPY are found to be higher than those of aza‐BODIPY. |
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| Keywords: | fluorescent probes phosphorus photophysical properties PODIPY water soluble |
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