Abstract: | A series of N-phenyl-3-methylthiopropylamine hydrochlorides were prepared by reacting a series of anilines with methional and sodium cyanoborohydride. These were cyclized upon oxidation by N-chloro-succinimide to the corresponding N-phenyl-S-methylisothiazolidinium derivatives which were isolated as the tetraphenylborate salts. Compounds successfully prepared included the m-methyl, p-methyl, m-methoxy, and p-methoxyphenyl derivatives. |