Nitrogen-15 NMR studies of 1,4-benzodiazepines: 2—The triazolobenzodiazepines

Nitrogen-15 NMR data for a series of 21 triazolobenzodiazepines are presented, including ¹⁵N chemical shifts and substituent effects. The line assignments made by correlation to other model compounds were confirmed by a shift reagent and protonation study. A Yb(dpm)₃ study on alprazolam showed that the molar shifts of the four nitrogens ranged from 35 to 150 ppm.