|
|||||
|
|
4-Azapteridines. I. Covalent addition products of the pyrazino[2,3-e]-as-triazine ring system |
|
| Authors: | Cherng Chyi Tzeng Raymond P Panzica |
| Abstract: | Ring closure of 5, 6-diamino-3-methylthio-as-triazine with 40% aqueous glyoxal provided the 6, 7-dihydrate of the pyrazino2, 3-e]-as-triazine (4-azapteridine) ring system. The C7 hydroxy group of this dihydrate underwent exchange in methanol or ethanol affording the 7-alkoxy, 6-hydroxy derivatives. |
| Keywords: | |