Abstract: | The chemical ionization mass spectra of different dicarboxylic acids, including saturated and unsaturated aliphatic, aromatic, hydroxyl and amino-substituted dicarboxylic acids, have been studied using pure methanol as the reagent gas. Biomolecular monoesterification and diesterification product ions M+15]+ and M+29]+, and adduct ion M+33]+, were observed, in addition to the protonated molecule MH]+ and unimolecular water elimination product ions. The formation of a protonated molecule with bridged intramolecular hydrogen bond, and its effect on the esterification of dicarboxylic acids is discussed. Geometric isomers, such as maleic and fumaric acid, and ortho and meta isomers of phthalic acids can be distinguished from each other by methanol chemical ionization mass spectra. When ethanol was used as the reagent gas, similar mass spectra of some dicarboxylic acids were obtained. |