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On the existence of regular structures in liquid human blood serum (plasma) and phase transitions in the course of its drying
Authors:T A Yakhno  O A Sedova  A G Sanin  A S Pelyushenko
Institution:(1) Institute of Applied Physics, Russian Academy of Sciences, Nizhni Novgorod, 603950, Russia
Abstract:Experimental data show that regular three-dimensional liquid-crystal protein structures ranging in size from several hundredths to several tenths of a millimeter are present in the whole blood serum (plasma) of patients suffering from various diseases. When a drop of serum dries, some of the structures melt to produce a gel, whereas the rest of them undergo phase transition to form solid crystals. These crystals are shaped like immunoglobulin M molecules enlarged 1000-fold. In the serum (plasma) of ailing people, the amount of the gel formed upon drying increases, breaking the symmetry during the formation of nonequilibrium protein films. It is believed that low-intensity physical factors exert a therapeutic action by changing the phase state of protein in body fluids.
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