| 低取代度两亲性β-环糊精及其水相中纳米球的制备 |
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| 引用本文： | 郭文彦,赵明刚,郝爱友. 低取代度两亲性β-环糊精及其水相中纳米球的制备[J]. 应用化学, 2013, 30(3): 260-264. DOI: 10.3724/SP.J.1095.2012.20164 |
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| 作者姓名： | 郭文彦 赵明刚 郝爱友 |
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| 作者单位： | (1.山西师范大学化学与材料科学学院 临汾 041004；2.山西师范大学现代文理学院 临汾 041000;3.山东大学化学与化工学院 济南 250100) |
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| 基金项目： | 教育部高等学校博士学科点专项科研基金资助(20091404110001) |
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| 摘 要： | 将2-O-(2-羟丙基)-β-环糊精与十二烷基、十四烷基、十六烷基和十八烷基缩水甘油醚在吡啶中反应，合成了4个低取代度的两亲性β-环糊精衍生物(平均取代度分别为1.87、1.95、2.14和1.80)。 将上述4个化合物分散于水中自组装成可稳定2~3周的纳米球，并且均呈现出较好的分散度和均匀性。
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| 关 键 词： | 两亲性 O-(羟丙基)-&beta -环糊精 缩水甘油醚 纳米球 |
| 收稿时间： | 2012-04-19 |
| 修稿时间： | 2012-06-12 |
Synthesis of Amphiphilic β-Cyclodextrins and Their Nanospheres in Water |
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| GUO Wenyan , ZHAO Minggang , HAO Aiyou. Synthesis of Amphiphilic β-Cyclodextrins and Their Nanospheres in Water[J]. Chinese Journal of Applied Chemistry, 2013, 30(3): 260-264. DOI: 10.3724/SP.J.1095.2012.20164 |
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| Authors: | GUO Wenyan ZHAO Minggang HAO Aiyou |
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| Affiliation: | (1.School of Chemistry and Materials Science,Shanxi Normal University,Linfen 041004,China;2.Modern College of Arts and Science of Shanxi Normal University,Linfen 041000,China;3.School of Chemistry and Chemical Engineering,Shandong University,Ji′nan 250100,China) |
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| Abstract: | Four amphiphilic bifunctionalized β-cyclodextrin derivatives with low degree of substitution(DS) were conveniently synthesized via the reaction of 2-O-(2-hydroxypropyl)-β-cyclodextrin with Lauryl glycidol ether, tetradecyl glycidol ether, hexadecyl glycidol ether and octadecyl glycidol ether in pyridine, respectively. The four amphiphilic β-CD derivatives(DS 1.87, 1.95, 2.14 and 1.80, respectively) could self-assemble in water to form stable nanospheres with improved dispersion degree and uniformity up to 2~3 weeks. |
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| Keywords: | amphiphilic O-(hydroxypropyl)-& beta -cyclodextrin glycidol ether nanospheres |
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