Anodic modification of proline derivatives using a lithium perchlorate/nitromethane electrolyte solution |
| |
Authors: | Kim Shokaku Hayashi Kanako Kitano Yoshikazu Tada Masahiro Chiba Kazuhiro |
| |
Affiliation: | Laboratory of Bio-organic Chemistry, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu, Tokyo 183-8509, Japan. |
| |
Abstract: | [reaction: see text] N-Acyliminium cation of prolines was efficiently generated to accumulate in an undivided cell at 0 degrees C by an anodic oxidation of N-acylprolines or alpha'-phenylsulfanylated N-acylproline derivatives in a lithium perchlorate/nitromethane solution. The iminium cation intermediates gave modified prolines by a reaction with nucleophiles under mild conditions. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|