| 流动相组成对有机硒手性化合物拆分的影响 |
| |
| 引用本文： | 韩小茜,齐邦峰,敦惠娟,祝馨怡,纳鹏君,蒋生祥,陈立仁. 流动相组成对有机硒手性化合物拆分的影响[J]. 色谱, 2002, 20(3): 241-244 |
| |
| 作者姓名： | 韩小茜 齐邦峰 敦惠娟 祝馨怡 纳鹏君 蒋生祥 陈立仁 |
| |
| 作者单位： | 中国科学院兰州化学物理研究所, 甘肃 兰州 730000 |
| |
| 基金项目： | 中国科学院重点基金 (批准号 :KY95 S1 2 0 5 ) |
| |
| 摘 要： | 在自制的涂敷型纤维素 三 (3,5 二甲基苯基氨基甲酸酯 ) (CDMPC)手性固定相上拆分了一些结构相似的有机硒手性化合物 ,详细考察了三元流动相对手性拆分的影响 ,并探讨了溶质分子与手性固定相相互作用的模式。实验结果表明 :在二元流动相中加入极少量的质子性改性剂 (醇 )或非质子性改性剂 (乙腈 ) ,可使溶质的保留和手性拆分发生较大的变化。
|
| 关 键 词： | 高效液相 纤维素三(3 5二甲基苯基氨基甲酸酯) 三元流动相 手性拆分 有机硒 |
| 文章编号： | 1000-8713(2002)03-0241-04 |
| 修稿时间： | 2001-10-30 |
Influence of Mobile Phase Composition on Chiral Separationof Organic Selenium Racemates |
| |
| HAN Xiao qian,QI Bang feng,DUN Hui juan,ZHU Xin yi,NA Peng jun,JIANG Sheng xiang,CHEN Li ren. Influence of Mobile Phase Composition on Chiral Separationof Organic Selenium Racemates[J]. Chinese journal of chromatography, 2002, 20(3): 241-244 |
| |
| Authors: | HAN Xiao qian QI Bang feng DUN Hui juan ZHU Xin yi NA Peng jun JIANG Sheng xiang CHEN Li ren |
| |
| Affiliation: | Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China. |
| |
| Abstract: | The chiral separation of some chiral compounds with similar structure on the cellulose tris (3,5 dimethylphenylcarbamate) chiral stationary phase prepared by us was obtained. Ternary mobile phases influencing chiral recognition were investigated. A mode of interaction between the structural character of samples and chiral stationary phase is discussed. The results indicated that the retention and chiral separation of the analytes had a bigger change with minute addition of alcohols or acetonitrile as modifier in n hexane/2 propanol (80/20,volume ratio) binary mobile phase. |
| |
| Keywords: | high performance liquid chromatography cellulose tris(3 5 dimethylphenylcarbamate) ternary mobile phase chiral separation organic selenium |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
| 点击此处可从《色谱》浏览原始摘要信息 |
|
点击此处可从《色谱》下载全文 |
