Synthesis and biological evaluation of rigid polycyclic derivatives of the Diels-Alder adduct tricyclo[6.2.1.02,7]undeca-4,9-dien-3,6-dione |
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| Authors: | Ito Felicia Megumi Petroni Jacqueline Marques de Lima Dênis Pires Beatriz Adilson Marques Maria Rita de Moraes Manoel Odorico Costa-Lotufo Letícia Veras Montenegro Raquel Carvalho Magalhães Hemerson Iury Ferreira Pessoa Cláudia do O |
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| Affiliation: | Department of Chemistry, Federal University of Mato Grosso do Sul, Campo Grande, MS, Brazil. megumi@nin.ufms.br |
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| Abstract: | Part of our research program concentrates on the discovery of new bioactive compounds prepared either by total synthesis or molecular transformation of compounds with bioactivity profiles. In this work we have focused our interest on chemical transformations of the Diels-Alder adduct tricyclo[6.2.1.0(2,7)]undeca-4,9-dien-3,6-dione in order to obtain cage-like compounds and derivatives, followed by an evaluation of their biological activity. |
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