Flow-injection determination of ornidazole by chemiluminescence detection based on a luminol-ferricyanide reaction. |
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| Authors: | Yi Lv Zhujun Zhang Deyong He Yufei Hu |
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| Affiliation: | Institute of Analytical Science, Department of Chemistry, Southwest Normal University, Beibei, Chongqing 400715, PR China. |
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| Abstract: | A flow-injection analysis (FIA) with a chemiluminescence detection method was developed for the determination of ornidazole based on the inhibition intensity of chemiluminescence from the luminol-ferricyanide system. Under the condition of 1.0 x 10(-3) mol/L luminol and 5.0 x 10(-6) mol/L potassium ferricyanide, the response to the concentration of omidazole is linear from 0.2 microg ml(-1) to 10 microg ml(-1), and a detection limit of 0.05 microg ml(-1) can be obtained. This method has been successfully applied to the determination of omidazole in pharmaceutical preparations. |
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