Distribution of aluminum species in normal urine as determined by chemical neutron activation analysis |
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Authors: | D M Shoop A J Blotcky E P Rack |
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Institution: | (1) Department of Veterans Affairs Medical Center, Research Service, 151C, 68105 Omaha, NE, USA;(2) Department of Chemistry, University of Nebraska, 68588 Lincoln, NE, USA |
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Abstract: | A procedure developed for separating and quantifying non protein and protein fractions of aluminum species in urine was applied
to four consecutive 24 hr collections of five healthy subjects. The total Al content of urine was determined by a chemical
neutron activation analysis technique reported elsewhere. Results from the analysis of all subjects indicate that the majority
of aluminum is bound to protein (>88%) with minor fractions as citrate complexes. These data are comparable with other speciation
experiments with blood plasma indicating 90% of the aluminum was bound to plasma proteins. |
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