Screening for crystalline salts via mechanochemistry |
| |
| Authors: | Trask Andrew V Haynes Delia A Motherwell W D Samuel Jones William |
| |
| Institution: | Pfizer Institute for Pharmaceutical Materials Science, Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, UKCB2 1EW. |
| |
| Abstract: | Neat grinding and solvent-drop grinding methods are found to be effective screening tools for indicating the potential for crystalline salt formation involving a given acid-base pair, as demonstrated with two model pharmaceuticals. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
