Experimental testing of the calculation results of the dissociation constants of organic compounds in nonaqueous media

27 Dissociation constants of carboxylic and NH-acids in methanol, ethanol and formamide were measured by potentiometric method. The selection of compounds for the analysis is determined by the preliminary computation of the constants by elemental linear empirical method, and also by the absence of the consistent published data on the values for the chosen compounds. The comparison of results showed that the obtained values of dissociation constants as a rule are consistent with those predicted in the range with the relative error of 10%.