The principle of parametric fractionation (separation) of substances in biological systems and technology

The parametric fractionation (separation) of substances is based on simultaneous exposure of a heterogeneous system with the phases (solid and liquid or liquid and gaseous) including components subject to be separated to the influence of two periodic fields of different nature. One field, “parameter” (for instance, temperature, pH) causes periodical redistribution of the components between phases, and the other field (for instance, mechanical forces, surface tension, electric field) effects synchronous shift of the components of one phase with respect to the other. As a result a counter flow of components to be separated formed against the gradient of their chemical or electrochemical potentials. This method underlain by the general principle of synchronous detection by no means is connected with definite mixtures or sorbents, it operates spontaneously in the inanimate and animate natural systems and can be applied to quite unexpected technologies.