激光血管外照射治疗可行性研究

为探讨激光血管外照射治疗的可行性,测试了人活体血管外照射以及模拟血管内照射的光能流率分布情况。研究表明,激光血管内、外照射的总光能流率的平均值分别为10.81W/cm²与1.11W/cm²,两者相差一个数量级。为获得血管内照射相应的光能流率,建议采用20mW632.8nmHe-Ne激光;垂直入射于人皮肤外表:尽可能选择血管暴露的病人或较为暴露的血管;选择被照射血管直径为6mm左右。本实验结果,特别是在人活体血管内探测到的实验数据,将有益于光在人体组织内传播特性的研究。

THE FEASIBILITY OF EXTERIOR VASCULAR LASER IRRADIATION THERAPY

In order to study the feasibility of exterior vascular laser irradiation therapy,we measure the distribution of radiant fluence rate in exterior vascular laser irradiation in vivo and imitative intravascular laser irradiation.The result shows that the average radiant fluence rate of exterior vascular and intravascular is 1.11 and 10.81 respectively,which is ten times between them.In order to get the radiant fluence rate corresponding to the intravascular laser irradiation,we suggest that about 20mW He Ne laser could be used in exterior vascular laser irradiation therapy,and the laser must irradiate on the vascular perpendicularly.The suitable patient with exposed vascular must be chosen,and the diameter of the irradiated vascular is about 6mm.Our experiment result,especially the data measured in vivo,will be useful for the research of light transport in human tissue.