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Surface modification of thermoplastic polyurethane in order to enhance reactivity and avoid cell adhesion
Authors:Patricia Alves  Jean-Pierre Kaiser  Janne Haack  Natalie Salk  Arie Bruinink  Hermínio C de Sousa  Maria Helena Gil
Institution:1.Department of Chemical Engineering,University of Coimbra,Coimbra,Portugal;2.EMPA. St. Gallen,St. Gallen,Switzerland;3.Mikrofertigung-Micro Engineering, Fraunhofer IFAM,Bremen,Germany
Abstract:Recently, the definition of coating procedures which leads to strong cell repellent surfaces has been an extremely important issue. In the present study, the cell repellency of thermoplastic polyurethane material (Elastollan®1180A50) surfaces was achieved by chemical treatment. Samples of Elastollan®1180A50 processed by injection molding, were oxidized with hydrogen peroxide (H2O2) and then impregnated with poly(ethylene glycol). The oxidation time was evaluated as were the effects of the PEG impregnation. Of all the evaluated modifications, a surface oxidation for 2 h, followed by impregnation with poly(ethylene glycol) resulted in the best cell repellent surface.
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