2-Allyloxy/propargyloxypyridines: synthesis,structure, and biological activity |
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| Authors: | E V Babaev Y I Koval V B Rybakov E G Paronikyan G M Stepanyan R G Paronikyan Sh Sh Dashyan S A Rzhevskii I A Shadrin |
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| Institution: | 1.Department of Chemistry,M. V. Lomonosov Moscow State University,Moscow,Russian Federation;2.A. L. Mnjoyan Institute of Fine Organic Chemistry of Scientific-Technological Center of Organic and Pharmaceutical Chemistry,National Academy of Sciences of the Republic of Armenia,Yerevan 26,Armenia |
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| Abstract: | The alkylation (allylation and propargylation) of 3-cyano-6-dialkylamino-2-pyridones containing a d-annulated ring occurs at the oxygen atom. The structures of the starting compounds and their alkylation products were determined by X-ray diffraction. The neurotropic and antimicrobial activity of alkylation products was examined. |
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