红外光谱监测聚富马酸二羟丙酯及其共聚物的合成研究

聚富马酸二羟丙酯(PPF)是一种可生物降解的线形不饱和聚合物，其分子链上的双键在适当引发剂的作用下可以与其他烯类单体进行交联，生成具有三维网络结构的交联体，对组织起到支撑作用。先合成了中间体低聚物-富马酸二羟丙酯(PFP)，然后采用熔融缩聚的方法通过低聚物PFP合成了聚合物PPF，并且在此基础上采用类似的方法合成了癸二酸二羟丙酯(PSP)，再使PFP和PSP进行缩聚反应，生成包含癸二酸二羟丙酯链段的新的聚富马酸二羟丙酯的共聚物——聚(富马酸二羟丙酯共聚癸二酸二羟丙酯)P(PF-co-PS)。在合成的过程中用FTIR对中间体富马酸二丙二醇酯、癸二酸二羟丙酯以及PPF和P(PF-co-PS)的结构进行了表征。结果表明，随着聚合反应的进行，低聚物逐渐转化为聚合物PPF或P(PF-co-PS)。

FTIR Study on the Synthesis of Poly(Propylene Fumarate) and Its Copolymer

Poly(propylene fumarate)(PPF)is one kind of linear biodegradable polyester and the unsaturated double bonds along its main chain can be crosslinked with other olefinic monomers to form three-dimensional networks,and the networks can support tissues.In the present paper,firstly,the intermediate oligomer-bis(2-hydroxypropyl)fumarate(PFP)was synthesized, and then the unsaturated linear polyester PPF was synthesized with the oligomer PFP through melting condensation process.Additionally, on the base of the proc...