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Metabolites from the endophytic fungi Botryosphaeria rhodina PSU-M35 and PSU-M114
Authors:Vatcharin Rukachaisirikul  Jiraporn Arunpanichlert  Souwalak Phongpaichit
Institution:a Department of Chemistry and Center for Innovation in Chemistry, Faculty of Science, Prince of Songkla University, Songkhla 90112, Thailand
b Department of Microbiology, Faculty of Science, Prince of Songkla University, Songkhla 90112, Thailand
c National Center for Genetic Engineering and Biotechnology (BIOTEC), Thailand Science Park, Klong Luang, Pathumthani 12120, Thailand
Abstract:Three dimeric γ-lactones (1-3), one dihydronaphthalene-2,6-dione (4), one hexahydroindenofuran (5), one cyclopentanone (6), and one lasiodiplodin (7) were isolated from the endophytic fungi Botryosphaeria rhodina PSU-M35 and PSU-M114 along with twelve known metabolites. The structures and the proposed stereochemistry of the new metabolites were established by spectral data analysis. The isolated compounds were submitted for evaluation of the antibacterial activity against Staphylococcus aureus, both standard and methicillin-resistant strains.
Keywords:Botryosphaeria rhodina  Dimeric γ-lactone  Hexahydroindenofuran  Antibacterial activity
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