The first total synthesis of aplysamine 6, an inhibitor of isoprenylcysteine carboxy methyltransferase |
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Authors: | Nisar Ullah Khaled M. Arafeh |
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Affiliation: | Chemistry Department, King Fahd University of Petroleum and Minerals, Dhahran 31261, Saudi Arabia |
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Abstract: | The first total synthesis of aplysamine 6, an inhibitor of isoprenylcysteine carboxy methyltransferase (Icmt), was accomplished in an overall high yielding reaction sequence. |
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Keywords: | Aplysamine 6 Icmt inhibitor Anticancer drug Chemoselective acylation |
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